Standard cylinder hand trucks are made from steel and come with a chain or strap to secure cylinders to the trucks. They are used for routine applications where cylinders need to be moved.

Ergonomic tilt-back cylinder hand trucks have two swivel casters mounted on a frame extension behind the trucks' two primary wheels. The hand trucks can rest on all four wheels when they are tilted back, which reduces the physical effort it takes to keep them upright when moving heavy cylinders. It also lets operators open doors and perform other tasks with their hands without having to support the hand trucks or return them to vertical and then re-tilt them again.

These hand trucks can transport oxygen and acetylene gas cylinders used in welding applications. They can also be used to store the cylinders for short periods of time (less than 24 hours). They may have features such as compartments, trays, or winders for storing welding equipment or hoses as well as brackets that secure specific sizes of welding gas cylinders.